7yg5 | pdb_00007yg5

Structure of human R-type voltage-gated CaV2.3-alpha2/delta1-beta1 channel complex in the topiramate-bound state

spinqualitylabelsall models 7yg5, resolution 3.00Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 7yg5 is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 3Å Ligands: 3PE, BMA, CA, NAG, R16, TOR, Y01 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease CA2D1_HUMAN Familial short QT syndrome;Brugada syndrome. Function CA2D1_HUMAN The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel. Plays an important role in excitation-contraction coupling (By similarity).

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