7dkn | pdb_00007dkn
From Proteopedia
Crystal structure of Sulfurisphaera tokodaii O6-methylguanine methyltransferase
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Structural highlights
FunctionOGT_SULTO Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated (By similarity). See AlsoContents | ||||||||||||||||||||
This page was last modified 16:35, 29 November 2023.