8ivd | pdb_00008ivd

COMPLEX STRUCTURE OF CD93-IGFBP7

spinqualitylabelsall models 8ivd, resolution 3.24Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 8ivd is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 3.24Å Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease IBP7_HUMAN Familial retinal arterial macroaneurysm. The disease is caused by variants affecting the gene represented in this entry. Function IBP7_HUMAN Binds IGF-I and IGF-II with a relatively low affinity. Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion. C1QR1_HUMAN Receptor (or element of a larger receptor complex) for C1q, mannose-binding lectin (MBL2) and pulmonary surfactant protein A (SPA). May mediate the enhancement of phagocytosis in monocytes and macrophages upon interaction with soluble defense collagens. May play a role in intercellular adhesion.

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