Structural highlights
7ae4 is a 12 chain structure with sequence from Sedimentibacter hydroxybenzoicus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
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| Method: | X-ray diffraction, Resolution 3.31Å |
| Ligands: | CL, EDO, MG, NA, PEG, PO4, ZN |
| Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT |
Function
YCLC_SEDHY Involved in the non-oxidative decarboxylation and detoxification of phenolic derivatives under anaerobic conditions (PubMed:10438791, PubMed:7744052, PubMed:24193968, PubMed:15979273). Oxygen-sensitive phenolic acid decarboxylase that catalyzes the reversible decarboxylation of 4-hydroxybenzoate and 3,4-dihydroxybenzoate (PubMed:10438791, PubMed:7744052, PubMed:15979273).[1] [2] [3] [4]
References
- ↑ Huang J, He Z, Wiegel J. Cloning, characterization, and expression of a novel gene encoding a reversible 4-hydroxybenzoate decarboxylase from Clostridium hydroxybenzoicum. J Bacteriol. 1999 Aug;181(16):5119-22. PMID:10438791 doi:10.1128/JB.181.16.5119-5122.1999
- ↑ Lupa B, Lyon D, Gibbs MD, Reeves RA, Wiegel J. Distribution of genes encoding the microbial non-oxidative reversible hydroxyarylic acid decarboxylases/phenol carboxylases. Genomics. 2005 Sep;86(3):342-51. PMID:15979273 doi:10.1016/j.ygeno.2005.05.002
- ↑ Zhang X, Wiegel J. Isolation and partial characterization of aClostridium species transforming para-hydroxybenzoate and 3,4-dihydroxybenzoate and producing phenols as the final transformation products. Microb Ecol. 1990 Dec;20(1):103-21. PMID:24193968 doi:10.1007/BF02543871
- ↑ He Z, Wiegel J. Purification and characterization of an oxygen-sensitive reversible 4-hydroxybenzoate decarboxylase from Clostridium hydroxybenzoicum. Eur J Biochem. 1995 Apr 1;229(1):77-82. PMID:7744052 doi:10.1111/j.1432-1033.1995.tb20440.x
