7nup | pdb_00007nup

Endoplasmic reticulum aminopeptidase 2 complexed with a mixed hydroxamic and sulfonyl ligand

spinqualitylabelsall models 7nup, resolution 3.10Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 7nup is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 3.1Å Ligands: BMA, BR, EDO, MAN, NAG, PGE, USK, ZN Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function ERAP2_HUMAN Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules. Preferentially hydrolyzes the basic residues Arg and Lys. See Also Aminopeptidase 3D structures

Proteopedia Page Contributors and Editors (what is this?)

OCA