4um9 | pdb_00004um9
From Proteopedia
Crystal structure of alpha V beta 6 with peptide
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Structural highlights
DiseaseTGFB3_HUMAN Defects in TGFB3 are a cause of familial arrhythmogenic right ventricular dysplasia type 1 (ARVD1) [MIM:107970; also known as arrhythmogenic right ventricular cardiomyopathy 1 (ARVC1). ARVD is an autosomal dominant disease characterized by partial degeneration of the myocardium of the right ventricle, electrical instability, and sudden death. It is clinically defined by electrocardiographic and angiographic criteria; pathologic findings, replacement of ventricular myocardium with fatty and fibrous elements, preferentially involve the right ventricular free wall.[1] FunctionTGFB3_HUMAN Involved in embryogenesis and cell differentiation. See AlsoReferences
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This page was last modified 07:47, 7 February 2024.