6ro2 | pdb_00006ro2

The crystal structure of a complex between the LlFpg protein, a THF-DNA and an inhibitor

spinqualitylabelsall models 6ro2, resolution 1.82Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 6ro2 is a 3 chain structure with sequence from Lactococcus cremoris and Synthetic construct. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 1.821Å Ligands: 2ON, 3DR, GOL Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function FPG_LACLC Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. See Also DNA glycosylase 3D structures

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