7r2m | pdb_00007r2m

SYNJ2BP complex with a synthetic Vangl2 peptide (9mer).

spinqualitylabelsall models 7r2m, resolution 2.40Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 7r2m is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.4Å Ligands: CA, GOL, PE4 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function A0A4W2GEM6_BOBOX Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response. Inhibits PCSK9-enhanced LDLR degradation, probably reduces PCSK9 protein levels via a translational mechanism but also competes with LDLR for binding with PCSK9.[ARBA:ARBA00003833]SYJ2B_HUMAN

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