5qis | pdb_00005qis

Covalent fragment group deposition -- Crystal Structure of OUTB2 in complex with PCM-0102500

spinqualitylabelsall models 5qis, resolution 1.53Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 5qis is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 1.53Å Ligands: EDO, J5G, PEG Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function OTUB2_HUMAN Hydrolase that can remove conjugated ubiquitin from proteins in vitro and may therefore play an important regulatory role at the level of protein turnover by preventing degradation. Mediates deubiquitination of both 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains, with a preference for 'Lys-63'-linked polyubiquitin chains. See Also Thioesterase 3D structures

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