8bw9 | pdb_00008bw9

Cryo-EM structure of the RAF activating complex KSR-MEK-CNK-HYP

spinqualitylabelsall models 8bw9, resolution 3.32Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 8bw9 is a 4 chain structure with sequence from Drosophila melanogaster. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 3.32Å Ligands: ANP, MG, QOM Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function AVE_DROME Required for normal photoreceptor differentiation between Ras and Raf for EGFR signaling in the eye and for mitogen-activated protein kinase phosphorylation. Probably acts together with Cnk to promote Raf activation, perhaps by recruiting an activating kinase.

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