4obv | pdb_00004obv

Ruminococcus gnavus tryptophan decarboxylase RUMGNA_01526 (alpha-FMT)

spinqualitylabelsall models 4obv, resolution 2.84Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4obv is a 4 chain structure with sequence from Ruminococcus gnavus ATCC 29149. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.84Å Ligands: 2SU, 3SO Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function TRPDC_RUMGV Catalyzes the decarboxylation of tryptophan to tryptamine. Tryptamine is a neurotransmitter that induces the release of serotonin, which is suggested to modulate gastrointestinal motility. Therefore, the tryptophan decarboxylase from the gut bacteria Ruminococcus gnavus (strain ATCC 29149 / VPI C7-9) may influence host brain and behavior. Has weak activity with tyrosine and phenylalanine.

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