5cuo | pdb_00005cuo

Structure of Rhodopseudomonas palustris PduL - CoA bound form

spinqualitylabelsall models 5cuo, resolution 1.54Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 5cuo is a 2 chain structure with sequence from Rhodopseudomonas palustris BisB18. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 1.544Å Ligands: COA, ZN Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function PDUL_RHOPB Involved in 1,2-propanediol (1,2-PD) utilization within the bacterial microcompartment (BMC) dedicated to 1,2-PD degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate. CoA is regenerated within the pdu BMC (for use by PduP) via this enzyme, although there must also be cofactor transport across the BMC (PubMed:26959993). Directly targeted to the BMC (By similarity). Phosphate is probably the first substrate to bind in the forward direction. CoA is probably the first substrate to bind in the reverse direction, and might bind to the enzyme as the BMC assembles, ensuring cofactor encapsulation (Probable).[UniProtKB:Q9XDN5]

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