5hi5 | pdb_00005hi5

Binding site elucidation and structure guided design of macrocyclic IL-17A antagonists

spinqualitylabelsall models 5hi5, resolution 1.80Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 5hi5 is a 7 chain structure with sequence from Homo sapiens and Synthetic construct. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 1.8Å Ligands: 63Q, ACE Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function IL17_HUMAN Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of ICAM1/intracellular adhesion molecule 1 in fibroblasts. See Also Interleukin 3D structures

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