5t8p | pdb_00005t8p

Crystal structure of murine NF-kappaB inducing kinase (NIK) bound to benzoxepin compound 2

spinqualitylabelsall models 5t8p, resolution 2.32Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 5t8p is a 2 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.32Å Ligands: 774, SO4 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function M3K14_MOUSE Lymphotoxin beta-activated kinase which seems to be exclusively involved in the activation of NF-kappa-B and its transcriptional activity. Promotes proteolytic processing of NFKB2/P100, which leads to activation of NF-kappa-B via the non-canonical pathway. Could act in a receptor-selective manner.

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