5u0s | pdb_00005u0s

Cryo-EM structure of the Mediator-RNAPII complex

Loading... Status: waiting for Mol* initialization Structural highlights 5u0s is a 10 chain structure with sequence from Schizosaccharomyces pombe. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 7.8Å Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function MED6_SCHPO Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. See Also Mediator

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