2d4a is a 4 chain structure with sequence from Aeropyrum pernix. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
MDH_AERPE Catalyzes the reversible oxidation of malate to oxaloacetate. Can also oxidize tartrate. Can utilize both NAD and NADP. Has a preference for NADP.[1]
Evolutionary Conservation
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
↑Kawakami R, Sakuraba H, Goda S, Tsuge H, Ohshima T. Refolding, characterization and crystal structure of (S)-malate dehydrogenase from the hyperthermophilic archaeon Aeropyrum pernix. Biochim Biophys Acta. 2009 Oct;1794(10):1496-504. Epub 2009 Jun 23. PMID:19555779 doi:10.1016/j.bbapap.2009.06.014
