6mrc | pdb_00006mrc
From Proteopedia
ADP-bound human mitochondrial Hsp60-Hsp10 football complex
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Structural highlights
DiseaseCH60_HUMAN Autosomal dominant spastic paraplegia type 13;Pelizaeus-Merzbacher-like disease due to HSPD1 mutation. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. FunctionCH60_HUMAN Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix. See Also | ||||||||||||||||||||
This page was last modified 14:44, 13 March 2024.