3skm | pdb_00003skm
From Proteopedia
Crystal structure of the HLA-B8FLRGRAYVL, mutant G8V of the FLR peptide
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Structural highlights
FunctionEBNA3_EBVG Plays an essential role for activation and immortalization of human B-cells. Represses transcription of viral promoters TP1 and Cp through interaction with host RBPJ, and inhibits EBNA2-mediated activation of these promoters. Since Cp is the promoter for all EBNA mRNAs, EBNA3A probably contributes to a negative autoregulatory control loop (By similarity). See AlsoContents | ||||||||||||||||||
This page was last modified 12:59, 14 March 2024.