3spg | pdb_00003spg

Inward rectifier potassium channel Kir2.2 R186A mutant in complex with PIP2

spinqualitylabelsall models 3spg, resolution 2.61Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 3spg is a 1 chain structure with sequence from Gallus gallus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.613Å Ligands: K, PIO Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function KCJ12_CHICK Inward rectifying potassium channel that is activated by phosphatidylinositol 4,5-bisphosphate and that probably participates in controlling the resting membrane potential in electrically excitable cells. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. The inward rectification is probably due to the blockage of outward current by cytoplasmic polyamines and/or magnesium ions. See Also Potassium channel 3D structures

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