3tmz | pdb_00003tmz

Crystal Structure of P450 2B4(H226Y) in complex with Amlodipine

spinqualitylabelsall models 3tmz, resolution 2.25Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 3tmz is a 1 chain structure with sequence from Oryctolagus cuniculus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.248Å Ligands: 06X, CM5, HEM Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function CP2B4_RABIT Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. In the epoxidation of arachidonic acid it has a unique preference for the 5,6-olefin. See Also Cytochrome P450 3D structures

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