3uv6 | pdb_00003uv6

Ec_IspH in complex with 4-hydroxybutyl diphosphate (1301)

spinqualitylabelsall models 3uv6, resolution 1.70Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 3uv6 is a 2 chain structure with sequence from Escherichia coli K-12. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 1.7Å Ligands: 0CH, SF4 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function ISPH_ECOLI Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Is also involved in penicillin tolerance and control of the stringent response. Seems to directly or indirectly interact with RelA to maintain it in an inactive form during normal growth. See Also 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 3D structures

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