4gc9 | pdb_00004gc9

Crystal structure of murine TFB1M in complex with SAM

spinqualitylabelsall models 4gc9, resolution 2.10Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4gc9 is a 1 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.103Å Ligands: ACT, MSE, SAM Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function TFB1M_MOUSE S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity (By similarity).

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