4gqs | pdb_00004gqs

Structure of Human Microsomal Cytochrome P450 (CYP) 2C19

spinqualitylabelsall models 4gqs, resolution 2.87Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4gqs is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.87Å Ligands: 0XV, GOL, HEM Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease CP2CJ_HUMAN Resistance to clopidogrel;Antidepressant or antipsychotics toxicity or dose selection;Voriconazole toxicity. Function CP2CJ_HUMAN Responsible for the metabolism of a number of therapeutic agents such as the anticonvulsant drug S-mephenytoin, omeprazole, proguanil, certain barbiturates, diazepam, propranolol, citalopram and imipramine. See Also Cytochrome P450 3D structures

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