3dwb | pdb_00003dwb

structure of human ECE-1 complexed with phosphoramidon

spinqualitylabelsall models 3dwb, resolution 2.38Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 3dwb is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.38Å Ligands: 5HD, RDF, ZN Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease ECE1_HUMAN Defects in ECE1 are a cause of Hirschsprung disease cardiac defects and autonomic dysfunction (HSCRCDAD) [MIM:613870. It is a form of Hirschsprung disease with skip-lesions defects, craniofacial abnormalities and other dysmorphic features, and autonomic dysfunction. Function ECE1_HUMAN Converts big endothelin-1 to endothelin-1. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

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