4ml0 | pdb_00004ml0

Crystal structure of E.coli DinJ-YafQ complex

spinqualitylabelsall models 4ml0, resolution 2.10Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4ml0 is a 16 chain structure with sequence from Escherichia coli B str. REL606. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.1Å Ligands: SO4 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function DINJ_ECOBD Antitoxin component of a type II toxin-antitoxin (TA) system (PubMed:24923448). A labile antitoxin that counteracts the effect of cognate toxin YafQ (PubMed:24923448). The YafQ-DinJ heterotetramer binds the consensus sequence 5'-TTTGAGCTACA-3' in the dinJ promoter; DinJ also binds DNA but not as well as the YafQ-DinJ complex (PubMed:24923448). Binding to the dinJ represses expression of the promoter (By similarity).[UniProtKB:Q47150]

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