1dis | pdb_00001dis

DIHYDROFOLATE REDUCTASE (E.C.1.5.1.3) COMPLEX WITH BRODIMOPRIM-4,6-DICARBOXYLATE

Loading... Status: waiting for Mol* initialization Structural highlights 1dis is a 1 chain structure with sequence from Lacticaseibacillus casei. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Solution NMR Ligands: BDM Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function DYR_LACCA Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also Dihydrofolate reductase 3D structures

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