1e8u | pdb_00001e8u

Structure of the multifunctional paramyxovirus hemagglutinin-neuraminidase

spinqualitylabelsall models 1e8u, resolution 2.00Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 1e8u is a 2 chain structure with sequence from Avian orthoavulavirus 1. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2Å Ligands: CA, NAG, SLB Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function HN_NDVK Attaches the virus to sialic acid-containing cell receptors and thereby initiating infection. Binding of HN protein to the receptor induces a conformational change that allows the F protein to trigger virion/cell membranes fusion (By similarity). Neuraminidase activity ensures the efficient spread of the virus by dissociating the mature virions from the neuraminic acid containing glycoproteins (By similarity). Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also Hemagglutinin 3D structures

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