1e9f | pdb_00001e9f

Mutant human thymidylate kinase complexed with TMP and ADP

spinqualitylabelsall models 1e9f, resolution 1.90Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 1e9f is a 1 chain structure with sequence from Escherichia coli and Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 1.9Å Ligands: ADP, MG, TMP Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function KTHY_HUMAN Catalyzes the conversion of dTMP to dTDP.KTHY_ECOLI Catalyzes the reversible phosphorylation of deoxythymidine monophosphate (dTMP) to deoxythymidine diphosphate (dTDP), using ATP as its preferred phosphoryl donor. Situated at the junction of both de novo and salvage pathways of deoxythymidine triphosphate (dTTP) synthesis, is essential for DNA synthesis and cellular growth. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also Thymidylate kinase 3D structures

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