Structural highlights
6kxk is a 8 chain structure with sequence from Arabidopsis thaliana. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
|
| Method: | X-ray diffraction, Resolution 2.5Å |
| Ligands: | CA, CL, EDO, GOL, PEG, PG4, PGE |
| Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT |
Function
BON1_ARATH Negative regulator of cell death and defense responses. Negative regulator of several R genes, including SNC1. May have effects in promoting growth and development. May function in membrane trafficking and in fusion of vesicles with plasma membrane at low temperature. Exhibits calcium-dependent phospholipid binding properties.[1] [2] [3] [4] [5]
References
- ↑ Yang S, Hua J. A haplotype-specific Resistance gene regulated by BONZAI1 mediates temperature-dependent growth control in Arabidopsis. Plant Cell. 2004 Apr;16(4):1060-71. PMID:15031411 doi:10.1105/tpc.020479
- ↑ Yang S, Yang H, Grisafi P, Sanchatjate S, Fink GR, Sun Q, Hua J. The BON/CPN gene family represses cell death and promotes cell growth in Arabidopsis. Plant J. 2006 Jan;45(2):166-79. PMID:16367962 doi:10.1111/j.1365-313X.2005.02585.x
- ↑ Lee TF, McNellis TW. Evidence that the BONZAI1/COPINE1 protein is a calcium defense suppressor. Plant Mol Biol. 2009 Jan;69(1-2):155-66. PMID:18855102 doi:10.1007/s11103-008-9413-6
- ↑ Li Y, Pennington BO, Hua J. Multiple R-like genes are negatively regulated by BON1 and BON3 in arabidopsis. Mol Plant Microbe Interact. 2009 Jul;22(7):840-8. PMID:19522566 doi:10.1094/MPMI-22-7-0840
- ↑ Li Y, Gou M, Sun Q, Hua J. Requirement of calcium binding, myristoylation, and protein-protein interaction for the Copine BON1 function in Arabidopsis. J Biol Chem. 2010 Sep 24;285(39):29884-91. PMID:20634289 doi:10.1074/jbc.M109.066100
