1n47 | pdb_00001n47

Isolectin B4 from Vicia villosa in complex with the Tn antigen

spinqualitylabelsall models 1n47, resolution 2.70Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 1n47 is a 4 chain structure with sequence from Vicia villosa. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.7Å Ligands: A2G, CA, FUC, MN, NAG, SER Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function LEC_VICVI N-acetyl-D-galactosamine specific lectin. Binds the Tn determinant (GalNAc-alpha-O-Ser/Thr) of the tumor-associated glycopeptide. Could be required for agglutinating cells such as Tn-exposed erythrocytes. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

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