1ls5 | pdb_00001ls5

Crystal structure of plasmepsin IV from P. falciparum in complex with pepstatin A

spinqualitylabelsall models 1ls5, resolution 2.80Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 1ls5 is a 4 chain structure with sequence from Plasmodium falciparum and Streptomyces argenteolus subsp. toyonakensis. This structure supersedes the now removed PDB entry 1jgf. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.8Å Ligands: IVA, STA Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function PLM4_PLAF7 During the asexual blood stage, catalyzes the cleavage of denatured host hemoglobin (Hb) (By similarity). Digestion of host Hb is an essential step which provides the parasite with amino acids for protein synthesis, and regulates osmolarity (Probable).[UniProtKB:Q17SB3] Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also Plasmepsin

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