1m9o | pdb_00001m9o
From Proteopedia
NMR structure of the first Zinc Binding domain of Nup475/TTP/TIS11
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Structural highlights
FunctionTTP_MOUSE mRNA-binding protein involved in post-transcriptional regulation of AU-rich element (ARE)-containing mRNAs. Acts by specifically binding ARE-containing mRNAs and promoting their degradation. Plays a key role in the post-transcriptional regulation of tumor necrosis factor (TNF).[1] Evolutionary Conservation![]() Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. References
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This page was last modified 08:33, 10 April 2024.