8y6i | pdb_00008y6i

P-glycoprotein in complex with UIC2 Fab and triple elacridar molecules in nanodisc

spinqualitylabelsall models 8y6i, resolution 2.54Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 8y6i is a 3 chain structure with sequence from Homo sapiens and Mus musculus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 2.54Å Ligands: 3PE, CLR, R0Z Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease MDR1_HUMAN Ulcerative colitis. Disease susceptibility is associated with variations affecting the gene represented in this entry. Function A0A1S4NYF2_BRALA MDR1_HUMAN Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.

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