1pth | pdb_00001pth

The Structural Basis of Aspirin Activity Inferred from the Crystal Structure of Inactivated Prostaglandin H2 Synthase

spinqualitylabelsall models 1pth, resolution 3.40Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 1pth is a 2 chain structure with sequence from Ovis aries. The May 2001 RCSB PDB Molecule of the Month feature on Cyclooxygenase by David S. Goodsell is 10.2210/rcsb_pdb/mom_2001_5. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 3.4Å Ligands: 0AH, BOG, HEM, NAG, SAL Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function PGH1_SHEEP May play an important role in regulating or promoting cell proliferation in some normal and neoplastically transformed cells. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also Cyclooxygenase 3D structures

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