8es7 | pdb_00008es7
From Proteopedia
CryoEM structure of PN45545 TCR-CD3 complex
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Structural highlights
DiseaseCD3Z_HUMAN Defects in CD247 are the cause of immunodeficiency due to defect in CD3-zeta (CD3ZID) [MIM:610163. An immunological deficiency characterized by T-cells impaired immune response to alloantigens, tetanus toxoid and mitogens.[1] FunctionCD3Z_HUMAN Probable role in assembly and expression of the TCR complex as well as signal transduction upon antigen triggering. See AlsoReferences
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This page was last modified 07:59, 1 May 2024.