1ut7 | pdb_00001ut7

Structure of the conserved domain of ANAC, a member of the NAC family of transcription factors

spinqualitylabelsall models 1ut7, resolution 1.90Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 1ut7 is a 2 chain structure with sequence from Arabidopsis thaliana. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 1.9Å Ligands: AU Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function NAC19_ARATH Transcription factors that bind specifically to the 5'-CATGTG-3' motif. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. Publication Abstract from PubMed The structure of the DNA-binding NAC domain of Arabidopsis ANAC (abscisic-acid-responsive NAC) has been determined by X-ray crystallography to 1.9A resolution (Protein Data Bank codes 1UT4 and 1UT7). This is the first structure determined for a member of the NAC family of plant-specific transcriptional regulators. NAC proteins are characterized by their conserved N-terminal NAC domains that can bind both DNA and other proteins. NAC proteins are involved in developmental processes, including formation of the shoot apical meristem, floral organs and lateral shoots, as well as in plant hormonal control and defence. The NAC domain does not possess a classical helix-turn-helix motif; instead it reveals a new transcription factor fold consisting of a twisted beta-sheet surrounded by a few helical elements. The functional dimer formed by the NAC domain was identified in the structure, which will serve as a structural template for understanding NAC protein function at the molecular level. Structure of the conserved domain of ANAC, a member of the NAC family of transcription factors.,Ernst HA, Olsen AN, Larsen S, Lo Leggio L EMBO Rep. 2004 Mar;5(3):297-303. PMID:15083810 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. See Also NAC transcription factor

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