7qqd | pdb_00007qqd

Nuclear factor one X - NFIX in P21

spinqualitylabelsall models 7qqd, resolution 2.70Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 7qqd is a 4 chain structure with sequence from Homo sapiens and Synthetic construct. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.7Å Ligands: EPE, ZN Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease NFIX_HUMAN Marshall-Smith syndrome;Malan overgrowth syndrome;19p13.3 microduplication syndrome. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. Function NFIX_HUMAN Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

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