Single-stranded DNA-binding protein

spinqualitylabelsall models E. coli SSB complex with ssDNA (stick model) and UMP 1eqq Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Single-stranded DNA-binding protein (SSB) binds to single-stranded regions of DNA (ssDNA) to protect it from annealing, prevention of secondary structure formation and digestion. SSB binds to DNA in a sequence-independent manner. The binding of SSB enables processes like replication, DNA repair and recombination to occur. SSB can form complexes with specific genome maintenance proteins helping their activities. Viral SSB proteins are monomeric. Eukaryotic SSB (Replication protein A – RPA) is a heterotrimer composed of RPA70, RPA32 and RPA14. RPA has 6 DNA-binding domains (DBD). Replication protein A70 is the eukaryotic SSB 70kDa subunit. Mitochondrial human SSB (HsmtSSB) is a homotetramer. See also Single stranded binding protein. 3D Structures of single-stranded DNA-binding protein Single-stranded DNA-binding protein 3D structures

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