2osn | pdb_00002osn

An alternate description of a crystal structure of phospholipase A2 from Bungarus caeruleus

spinqualitylabelsall models 2osn, resolution 2.50Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 2osn is a 1 chain structure with sequence from Bungarus caeruleus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.5Å Ligands: CL Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function PA2B3_BUNCE Snake venom phospholipase A2 (PLA2) that shows anticoagulant and neurotoxic activities. PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides (By similarity). Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. Publication Abstract from PubMed Reinterpretations of the space-group symmetry are reported for two crystal structures of phospholipase A(2) isoforms (PDB codes 1u4j and 1g2x). The two structures reported in space groups R3 and C2 are isomorphous with a third isoform with space group R32 (PDB code 1fe5). The original structure reports were interpreted in terms of different oligomeric forms of the isoforms, but these conclusions are not supported by the isomorphous structures. An alternate description of two crystal structures of phospholipase A2 from Bungarus caeruleus.,Le Trong I, Stenkamp RE Acta Crystallogr D Biol Crystallogr. 2007 Apr;63(Pt 4):548-9. Epub 2007, Mar 16. PMID:17372360 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. See Also Phospholipase A2 3D structures

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