3qo6 | pdb_00003qo6

Crystal structure analysis of the plant protease Deg1

spinqualitylabelsall models 3qo6, resolution 2.50Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 3qo6 is a 9 chain structure with sequence from Arabidopsis thaliana and Unidentified. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.5Å Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function DEGP1_ARATH Serine protease that is required at high temperature. May be involved in the degradation of damaged proteins. In vivo, can degrade beta-casein. Publication Abstract from PubMed Deg1 is a chloroplastic protease involved in maintaining the photosynthetic machinery. Structural and biochemical analyses reveal that the inactive Deg1 monomer is transformed into the proteolytically active hexamer at acidic pH. The change in pH is sensed by His244, which upon protonation, repositions a specific helix to trigger oligomerization. This system ensures selective activation of Deg1 during daylight, when acidification of the thylakoid lumen occurs and photosynthetic proteins are damaged. Structural adaptation of the plant protease Deg1 to repair photosystem II during light exposure.,Kley J, Schmidt B, Boyanov B, Stolt-Bergner PC, Kirk R, Ehrmann M, Knopf RR, Naveh L, Adam Z, Clausen T Nat Struct Mol Biol. 2011 Jun;18(6):728-31. Epub 2011 May 1. PMID:21532594 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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