9h2d | pdb_00009h2d

Human IFT172 C-terminal U-box domain crystal structure

spinqualitylabelsall models 9h2d, resolution 2.10Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 9h2d is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.097Å Ligands: CL, EPE Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease IF172_HUMAN Bardet-Biedl syndrome;Jeune syndrome;Retinitis pigmentosa;Saldino-Mainzer syndrome. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. Function IF172_HUMAN Required for the maintenance and formation of cilia. Plays an indirect role in hedgehog (Hh) signaling, cilia being required for all activity of the hedgehog pathway (By similarity).

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