8pkn | pdb_00008pkn

CryoEM structure of catalytic domain of human HMG-CoA reductase with its inhibitor atorvastatin

spinqualitylabelsall models 8pkn, resolution 2.26Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 8pkn is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 2.26Å Ligands: 117 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function HMDH_HUMAN Transmembrane glycoprotein that is the rate-limiting enzyme in cholesterol biosynthesis as well as in the biosynthesis of nonsterol isoprenoids that are essential for normal cell function including ubiquinone and geranylgeranyl proteins.

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