8fxz | pdb_00008fxz

Cryo-EM structure of cowpox virus M2 in complex with human B7.1 (heptameric ring)

spinqualitylabelsall models 8fxz, resolution 2.86Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 8fxz is a 14 chain structure with sequence from Cowpox virus (Brighton Red) and Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 2.86Å Ligands: NAG Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function Q8QN22_CWPXB Plays a role in immune evasion. When secreted, inhibits T-cell activation by preventing the binding of host CD80 and CD86 to soluble CTLA4 and CD28. In the infected cell, may inhibits host NF kappa B activation.[ARBA:ARBA00045309]

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