8ycx | pdb_00008ycx

CryoEM structure of M. tuberculosis ClpC1P1P2 complex bound to bortezomib, conformation 2

spinqualitylabelsall models 8ycx, resolution 2.20Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 8ycx is a 21 chain structure with sequence from Bos grunniens and Mycobacterium tuberculosis H37Rv. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 2.2Å Ligands: ADP, ATP, BO2, MG Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function CLPC1_MYCTU ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity). Degrades anti-sigma-E factor RseA in the presence of ClpP2.

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