7cgp | pdb_00007cgp

Cryo-EM structure of the human mitochondrial translocase TIM22 complex at 3.7 angstrom.

spinqualitylabelsall models 7cgp, resolution 3.70Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 7cgp is a 15 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 3.7Å Ligands: PEE Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease TIM22_HUMAN The disease is caused by variants affecting the gene represented in this entry. Function TIM22_HUMAN Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps (By similarity).[UniProtKB:Q12328] See Also Diacylglycerol kinase 3D structures

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