Dopamine receptor 3D structures

Updated on 28-April-2025

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• Dopamine receptor D1
  • 7joz – hDR D1/endolysin + guanine nucleotide-binding protein + nanobody + antgonist
    
  • 7ckw, 7ckx, 7cky, 7jv5, 7jvp – hDR D1 + guanine nucleotide-binding protein + nanobody + cholesterol + antagonist – Cryo EM
    
  • 8jxr, 8jxs – hDR D1 (mutant) + guanine nucleotide-binding protein + nanobody + antibody + LSD – Cryo EM
    
  • 7ckz – hDR D1 + guanine nucleotide-binding protein + nanobody + cholesterol + dopamine – Cryo EM
    
  • 7f24 – hDR D1 + guanine nucleotide-binding protein + GTP – Cryo EM
    
  • 7crh – hDR D1 + guanine nucleotide-binding protein + inhibitor – Cryo EM
    
  • 7x2f – hDR D1 in mini-GS complex + dopamine + cholesterol + quinolone derivative – Cryo EM
    
  • 7ljc, 7ljd – hDR D1 + GS protein + guanine nucleotide-binding protein + nanobody + cholesterol + dopamine – Cryo EM
    
  • 7jvq – hDR D1 + mini-GI protein + guanine nucleotide-binding protein + nanobody + cholesterol + apomorphine – Cryo EM
    
  • 7x2c, 7x2d, 8irr – hDR D1 in mini-Gs complex + nanobody + drug – Cryo EM
    
  • 7f1o, 7f23 – hDR D1 in mini-Gs complex + nanobody + GTP – Cryo EM
    
  • 7f1z – hDR D1 in mini-Gs complex + GDP – Cryo EM
    
  • 7f0t – hDR D1 in mini-Gs complex + dopamine – Cryo EM
    
• Dopamine receptor D1beta
  • 8irv – hDR D1B/cytochrome b-562 in mini-Gs complex + drug – Cryo EM
    
• Dopamine receptor D2
  • 6cm4 – hDR D2/endolysin + risperidone - human
    
  • 6luq – hDR D2/endolysin + piperidine derivative
    
  • 7dfp – hDR D2/cytochrome b562 + spiperone
    
  • 5aer – hDR D2 + neuronal calcium sensor
    
  • 6vms – hDR D2/endolysin + guanine nucleotide-binding protein + ScFv + bromocyptine – Cryo EM
    
  • 7jvr – hDR D2/cytochrome b562 + guanine nucleotide-binding protein + ScFv + bromocyptine – Cryo EM
    
  • 8irs – hDR D2 in mini-Gs complex + nanobody + drug – Cryo EM
    
  • 8u02 – hDR D2 in mini-Gs complex + dopamine – Cryo EM
    
  • 8tzq – hDR D2 in mini-Gs complex + ScfV + dopamine – Cryo EM
    
• Dopamine receptor D3
  • 3pbl – hDR D3/lysozyme  + eticlopride
    
  • 7cmv – hDR D3/cytochrome b562 + guanine nucleotide-binding protein + ScFv – Cryo EM
    
  • 7cmu, 8irt – hDR D3/cytochrome b562 + guanine nucleotide-binding protein + ScFv + drug – Cryo EM
    
• Dopamine receptor D4
  • 5wiu, 5wiv – hDR D4/cytochrome b562 + nemonapride
    
  • 6iql – hDR D4/cytochrome b562 + ligand
    
  • 8iru – hDR D4 in mini-Gs complex + nanobody + drug – Cryo EM
    

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel