FKBP 3D structures

3D Structures of FKBP

Updated on 03-July-2025

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• FKBP
  • 1fkr, 1fks, 1fkt – hFKBP - human - NMR
    
  • 1bl4 – hFKBP (mutant)+inhibitor
    
  • 1bkf – hFKBP (mutant)+FK-506
    
  • 1fkf - hFKBP+FK-506
    
  • 7dki – FKBP - silk worm
    
  • 1fks, 1fkr, 1fkt – EcFKBP – Escherichia coli
    
  • 1q6h, 1q6u – EcFKBP
    
  • 1q6i – EcFKBP+FK-506
    
  • 1ix5 – FKBP – Methanothermococcus thermolithotrophicus – NMR
    
• FKBP1B
  • 4iq2, 4iqc - hFKBP-1B (mutant)
    
  • 4c02 - hFKBP-1B+ activin receptor type I
    
  • 5tap, 6jgz, 6jh6, 6jhn, 6ji0, 6jrr, 6pv6, 6w1n, 6wot, 6wou, 6wov, 6x34, 7cf9, 7jmf, 7jmg, 7jmh, 7jmi, 7jmj - hFKBP-1B + ryanodine receptor type I – Cryo EM
    
  • 6ji8, 6jii, 6jiu, 6jiy, 6jrs, 6m2w, 6x32, 6x33, 6x35, 6x36 - hFKBP-1B + ryanodine receptor type I + calmodulin 1 – Cryo EM
    
  • 8z28, 8z38 - FKBP-1B – Pyricularia oryzae
    
• FKBP3
  • 3kz7 – hFKBP FK506-binding domain + immunosuppressant - human
• FKBP8
  • 2awg, 2f2d, 3ey6 - hFKBP FK506-binding domain
    
  • 2d9f – hFKBP – NMR
    
  • 2mf9 – hFKBP N terminal 58-206 – NMR
    
• FKBP12 or PPIase FKBP1A
  • 1d6o, 1fkk, 2dg3, 2ppn, 2ppp, 8x6p – hFKBP
    
  • 1eym, 2ppo, 4ipx, 4n19 – hFKBP (mutant)
    
  • 2gaq, 2pnu – hFKBP - NMR
    
  • 3uqi – ymFKBP – yellowfever mosquito
    
  • 2lpv – ymFKBP - NMR
    
  • 5ht1 – CgFKBP – Candida glabrata
    
  • 5htg, 5hw6, 5hw7 – CaFKBP – Candida albicans
    
  • 5i98 – CaFKBP (mutant)
    
  • 5hwb – NfFKBP – Neosartorya fumigata
    
  • 5j6e – NfFKBP (mutant)
    
  • 6vsi – FKBP – Candida auris
    
• FKBP12 complex
  • 1fkd, 1fkj, 1qpf, 1qpl, 2fke – hFKBP + immunosuppressant
    
  • 1j4h, 1j4i, 9lyg – hFKBP + inhibitor
    
  • 8chi, 8chj, 8chk, 8chl, 8chm, 8pdf – hFKBP (mutant) + inhibitor
    
  • 9dcw – hFKBP + macrocycle molecular glue
    
  • 1b6c – hFKBP + TGF-B superfamily receptor I
    
  • 3fap – hFKBP + FKBP12-rapamycin associated protein
    
  • 4fap - hFKBP + FKBP12-rapamycin associated protein + immunosuppressant
    
  • 1c9h, 1fkb, 2dg4, 4dh0 - hFKBP+rapamycin
    
  • 2dg9, 7u8d - hFKBP (mutant)+rapamycin
    
  • 1fap, 1nsg, 2fap - hFKBP+rapamycin+FRB
    
  • 1f40 – hFKBP +GPI-1046
    
  • 1a7x – hFKBP +FK-1012
    
  • 1d7h, 1d7i, 1d7j, 1fkg, 1fkh, 1fki – hFKBP +ligand
    
  • 6vcu, 6yf0, 6yf1, 6yf2, 6yf3 – hFKBP + drug
    
  • 8er6, 8er7 – hFKBP + serine/threonine protein kinase 224-317 + inhibitor
    
  • 6m4u, 8ppz – hFKBP + serine/threonine protein kinase MTOR peptide
    
  • 2rse – hFKBP + serine/threonine protein kinase MTOR peptide + rapamycin - NMR
    
  • 8era – hFKBP + serine/threonine protein kinase MTOR + LST8 – Cryo EM
    
  • 6m4v, 6m4w – hFKBP + MBP + rapamycin
    
  • 3h9r, 6i1s, 8pod – hFKBP + activin receptor type I
    
  • 3mdy – hFKBP+ BMPR1B
    
  • 1j4r – hFKBP + FKB-001
    
  • 6oqa – hFKBP + CEP250
    
  • 7m6a, 7m6l, 7vml, 7vmm, 7vmn, 7vmo, 7vmp, 7vmq, 7vmr, 7vms, 7u0s, 7u8d, 7u9q, 7u9r, 7u9t, 7u9x, 7u9z, 7ua1, 7ua3, 7ua4, 7ua5, 7ua9 - hFKBP + ryanodine receptor type 2 – Cryo EM
    
  • 1tco - bFKBP + Ser/Thr phosphatase B2 + immunosuppressant - bovine
    
  • 1fkl – bFKBP +rapamycin
    
  • 1yat – FKBP + antagonist – yeast
    
  • 5hua – CgFKBP + FK506
    
  • 5hw8 – CaFKBP (mutant) + FK506
    
  • 6tz6 – CaFKBP + FK506 + calcineurin B + serine/threonine protein phosphatase
    
  • 6vcv - NfFKBP + FK506 analog
    
  • 5hwc – NfFKBP (mutant) + FK506
    
  • 6tz7 – NfFKBP + FK506 + calcineurin B + serine/threonine protein phosphatase
    
  • 6tz8 – FKBP + FK506 + calcineurin B + serine/threonine protein phosphatase – Cryptococcus neoformans
    
  • 6vct, 6vrx – FKBP + FK506 analog – Mucor circinelloides
    
• FKBP12.6
  • 5hkg – hFKBP
    
  • 7t64, 7t65, 7tzc, 8dty, 8dtz, 8dvv, 9cgp, 9cgq - rFKBP + ryanodine receptor type 1 – Cryo EM
    
• FKBP13
  • 2pbc – hFKBP
    
  • 4nnr – hFKBP + FK506
    
  • 1u79, 1y0o – AtFKBP - Arabidopsis thaliana
• FKBP14
  • 4dip, 4msp – hFKBP
    
• FKBP22
  • 3b09 – FKBP N terminal - Shewanella
    
• FKBP25
  • 2mph – hFKBP
    
  • 2kfv – hFKBP N terminal 20-92
    
  • 1pbk – hFKBP C terminal
    
  • 5d75 – hFKBP + FK506
    
  • 5gpg – hFKBP FK1 domain + rapamycin + MTOR
    
• FKBP26
  • 3pr9, 3pra, 3prb, 3prd – FKBP – Methanocaldococcus jannaschii
• FKBP35
  • 2vn1 – PfFKBP FK1 domain+FK506
    
  • 4j4n – PfFKBP FK1 domain + antimalarial drug
    
• FKBP36
  • 3b7x – hFKBP
    
  • 5mgx – hFKBP + Hsp90 C-terminal
    
• FKBP38
  • 2mf9 - hFKBP N terminal - NMR
• FKBP39
  • 4ca9 - FKBP N terminal – Drosophila melanogaster – NMR
    
• FKBP42
  • 2f4e – AtFKBP N-terminal
    
  • 2if4 – AtFKBP
    
• FKBP51 or PPIase FKBP5; Domains – FK1 1-140; FK2 141-260
  • 1kt1, 5omp – hFKBP
    
  • 1kt0 – hFKBP (mutant)
    
  • 5njx – hFKBP + Hsp90 peptide
    
  • 7l7i – hFKBP + Hsp90 + P23 – Cryo EM
    
  • 3o5d – hFKBP FK1+FK2 domains
    
  • 3o5e, 3o5f, 3o5g, 3o5i, 3o5j, 3o5k - hFKBP FK1 domain
    
  • 3o5l, 3o5m, 3o5o, 3o5p, 3o5q, 4r0x - hFKBP FK1 domain (mutant)
    
  • 4lax – hFKBP FK1+FK2 domains + FK506
    
  • 4lay – hFKBP FK1+FK2 domains + I63
    
  • 3o5r - hFKBP FK1 domain (mutant) + immunosuppressant
    
  • 4drq, 5obk, 7a6w, 7a6x, 7aot, 7aou, 7apq, 7aps, 7apt, 7apw, 7awf, 7awx, 7b9y, 7b9z, 7ba0, 8chn, 8chp, 8chq, 8chr, 9eu6, 9eu7, 9eu8 9eu9, 9eua, 9eub, 9euc, 9eud, 9eue, 9ey3, 9ey4 – hFKBP FK1 domain + inhibitor
    
  • 4jfi, 4jfj, 4jfk, 4jfl, 4jfm, 4tw6, 4tw7, 4tx0, 4w9o, 4w9p, 4w9q, 5dit, 5diu, 5div, 7r0l, 8ba6, 8baj, 8cca, 8ccb, 8ccd, 8cce, 8ccf, 8ccg, 8cch, 8pj8, 8pja, 8r5k – hFKBP FK1 domain (mutant) + inhibitor
    
  • 9gpk, 9gpl, 9gpm, 9gpn, 9gpo, 9gpp, 9gpq, 9gpr, 9gps, 9gpt, 9gpu, 9gpv, 9gpw, 9gpx, 9gpy, 9gpz, 9gq2, 9gq3, 9gq4, 9gq5, 9gq6, 9gq7, 9gq8, 9gq9, 9gqa, 9gqb, 9gqc, 9gqd, 9gqe, 9gqf, 9gqg, 9gqh, 9gqi, 9gqj, 9gqk – hFKBP FK1 domain (mutant) + macrocyclic inhibitor
    
  • 4drk, 4drm, 4drn, 4dro, 4drp – hFKBP FK1 domain + FK506 analog
    
  • 7ett, 7etu, 7etv – hFKBP FK1 domain (mutant) + peptide inhibitor
    
  • 5bxj – hFKBP FK1 domain (mutant) + nitrophenol
    
  • 4tw8 – hFKBP FK1+FK2 domains (mutant) + inhibitor
    
  • 4drk, 4drm, 4drn, 4dro, 4drp – hFKBP FK1 domain + FK506 analog
    
  • 8era – hFKBP FK1 domain + serine/threonine protein kinase MTOR + TORC + raptor – Cryo EM
    
  • 4drh, 4dri – hFKBP FK1 domain + serine/threonine protein kinase MTOR peptide + rapamycin
    
  • 6tx4 – hFKBP FK1 domain + pyridone
    
  • 6tx6 – hFKBP FK1 domain + nicotinamide
    
  • 6tx5, 6tx8 – hFKBP FK1 domain (mutant) + imidazole derivative
    
  • 6tx7 – hFKBP FK1 domain (mutant) + piperidone derivative
    
  • 6tx9 – hFKBP FK1 domain (mutant) + hydantoin derivative
    
  • 6saf, 6txx – hFKBP FK1 domain (mutant) + ligand
    
  • 8pc2 – hFKBP FK1 domain (mutant) + seldeg51 + pvhl + elongin B + elongin C
    
  • 8ffw – hFKBP + Hsp90 peptide + glucocorticoid receptor – Cryo EM
• FKBP52 or PPIase FKBP4
  • 8ffv – hFKBP + Hsp90 peptide + glucocorticoid receptor – Cryo EM
  • 4lav, 4law – hFKBP FK1+FK2 domains 16-260
    
  • 1n1a, 1q1c – hFKBP N terminal 1-140
    
  • 1p5q - hFKBP C terminal 144-458
    
  • 4drj – hFKBP FK1 domain + serine/threonine protein kinase MTOR peptide + rapamycin
    
  • 6rcy – hFKBP FK1 domain + ligand
    
  • 1qz2 – hFKBP C-terminal + Hsp90 peptide
    
• FKBP53
  • 8zaj – AtFKBP nucleoplasmin domain 1-100 – Cryo EM
• FKBP59
  • 1rot, 1rou – FKBP N terminal – NMR – rabbit
  • 2lgo – FKBP – NMR – Giardia lamblia
• FKBP73
  • 3jxv, 3jym - FKBP - wheat
• SlyD

See Peptidyl-prolyl cis-trans isomerase

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Michal Harel, Openfox