9hdg | pdb_00009hdg

The structure of the catalytic domain of AfAA11B from the filamentous fungus Aspergillus fumigatus

spinqualitylabelsall models 9hdg, resolution 1.26Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 9hdg is a 1 chain structure with sequence from Aspergillus fumigatus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 1.26Å Ligands: ASC, CU, NAG, SO4 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function LP11B_ASPFU Lytic polysaccharide monooxygenase (LPMO)-like protein that acts as a strict peroxygenase and does not catalyze a monooxygenase reaction (PubMed:34567832). It is indeed hardly active on chitin, while being very active on soluble oligomers of N-acetylglucosamine (PubMed:34567832). Cleaves the glycosidic bonds byoxidizing the C1 position (PubMed:34567832). Also unable to oxidize cellopentaose (PubMed:34738811). Probably breaks glycosidic bonds in non-polymeric substrates possibly carbohydrates in the cell wall of the fungus or its competitors (PubMed:34567832). In the presence of chitotetraose, the enzyme can withstand considerable amounts of H(2)O(2), which it uses to efficiently and stoichiometrically convert this substrate (PubMed:34567832).

Proteopedia Page Contributors and Editors (what is this?)

OCA