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Structural highlights
Function
CF161_MOUSE Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating.[1] [2] [3]
References
- ↑ Zhou L, Liu H, Liu S, Yang X, Dong Y, Pan Y, Xiao Z, Zheng B, Sun Y, Huang P, Zhang X, Hu J, Sun R, Feng S, Zhu Y, Liu M, Gui M, Wu J. Structures of sperm flagellar doublet microtubules expand the genetic spectrum of male infertility. Cell. 2023 Jun 22;186(13):2897-2910.e19. PMID:37295417 doi:10.1016/j.cell.2023.05.009
- ↑ Chen Z, Shiozaki M, Haas KM, Skinner WM, Zhao S, Guo C, Polacco BJ, Yu Z, Krogan NJ, Lishko PV, Kaake RM, Vale RD, Agard DA. De novo protein identification in mammalian sperm using in situ cryoelectron tomography and AlphaFold2 docking. Cell. 2023 Oct 19:S0092-8674(23)01038-3. PMID:37865089 doi:10.1016/j.cell.2023.09.017
- ↑ Tai L, Yin G, Huang X, Sun F, Zhu Y. In-cell structural insight into the stability of sperm microtubule doublet. Cell Discov. 2023 Nov 21;9(1):116. PMID:37989994 doi:10.1038/s41421-023-00606-3
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