9ooo | pdb_00009ooo

Human delta 2 receptor with R710W Cerebellar Ataxia mutation in the apo closed state

spinqualitylabelsall models 9ooo, resolution 3.68Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 9ooo is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 3.68Å Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease GRID2_HUMAN Autosomal recessive congenital cerebellar ataxia due to GRID2 deficiency. The disease is caused by mutations affecting the gene represented in this entry. Function GRID2_HUMAN Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists.

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